| Discmedia Cape | Cape Town | cd/dvd duplication/printing blu ray printing | |
| Discount Autobody | Johannesburg | Your One Stop Autobody Repair Centre | |
| Discount Factory Shops | Cape Town | Retail Information Portal | |
| Discover & Take a Break Advertising Agency | Port Edward | Social Media Marketing | |
| Discover Tours & Safaris | White River | Safaris in Kruger National Park | |
| Discovit Media Productions | Umhlanga | Video Productions,TV & Promotional Productions | |
| DiscSpeed | Midrand | CD/DVD Duplication Equipment,Epson, Brother Canon | |
| Dishsat Eletronics | Johannesburg | HVAC, DSTV, CCTV, Gate Motors, Alarms, E.Fence | |
| Disko | Cape Town | Animation, 3D | |
| Display Company | Randburg | Suppliers of store fixtures & fittings | |
| Display Concepts | Johannesburg | Store Fixtures Shopfitting Rails Mannequins | |
| Display Mania International | Cape Town | Snap Frames, Pull-Up Banners, Light Boxes, Gazebos | |
| Displaypickers | | seo | |
| Displayworx | Jhb | Exhibitions (Co , Branding , Design n manufacture | |
| DIsrupt Media | Durban | Corporate Communication, Video Production | |
| Dissertation Writing Help | | Assignment Writing | |
| Distance Education school .com | delhi | Distance Education | |
| Distancecalculator.Io | | Distance | |
| Distillique | Pretoria | Training in Distillation and Alcohol Manufacturing | |
| Distinctive Choice t/a Lie and Tell | Cape Town | Truth Verification | |
| Distinctive Group | Midrand | General construction and maintenance | |
| Distinctive Moves | Cape Town | Removals | |
| Distribution Management Services | Cape Town | Business Management Consultant | |
| Ditas Cabling | Johannesburg | cctv ,network cabling,pabx an optic fiber | |
| Ditiro Events and Decor | Kempton Park | Ditiro Events & Decor Pty Ltd | |
| Ditlou Media | Johannesburg | Computer sales and Network support | |
| DivCoders | Johannesburg | Software Development | |
| Diverge Talent Management | Johannesburg | Modeling Agency | |
| Diverse Auto and Truck | Johannesburg | We buy company redundant vehicles | |
| Diverse Energy | Durban | Backup Energy | |
| Diversity Technology | Johannesburg | Training of machine operators | |
| Diversity Training in South Africa | Durban | Team Building Team Conflict Res Diversity Training | |
| DiversityTechnology Training Lnstitute | Johannesburg | Training and Development Center | |
| Divine Brand Intervention | Cape Town | Packaging Design, Corporate Indentity, POS design | |
| Divine Favour Progressive College FET | Pretoria | College | |
| Divine Locks Complex Reviews | | Health | |
| DivingWorld | Benoni | Underwater, Photographic, Camping, Luxury, 4x4, He | |
| Divorce Lawyers Cape Town | Cape Town, | Divorce Lawyers Cape Town | |
| Diy Book Binding Supplies | Durban | Diy Book Binding Supplies offers a wide range of b | |
| DIY Depot Bloemhof | Bloemhof | Direct marketing | |
| DIY Superstore | Bloemfontein | Building Materials | |
| DIYgirls Interior | Sandton | A one-stop interior design studio | |
| DIYweb4U | Johannesburg | DIY Website Builder | |
| DJ MrEdwards | JHB | Professional DJ for all occasssions | |
| DJ's Model Agency | Cape Town | Casting Agency | |
| DJJ Lemmer Labour Relations | Pta | Labour law | |
| Djjaani | | djjaani | |
| DJM CONCEPTS | PRETORIA | Broadcasting Streaming Recording & LED screens | |
| DK EXPRESSIONS™ | Johannesburg | Digital Media, PR, Marketing & Entertainment Servi | |
| Dlitraining | | graphic design | |
| Dlloyd Creative Enterprises | Johannesburg | Digital Printing and Barcoding | |
| Dlokodla Projects pty () | Johannesburg | supply domestic goods, constructions tools local | |
| DLPHOTO | Cape Town | Photography School & Studio | |
| Dlphoto Photo Studios | CAPE TOWN | Photography services | |
| Dludlu Brothers | Gauteng | Logistic soluthion | |
| DM Consortium | Kempton PArk | Office Consumables, Stationery & Hygiene | |
| DM Office Solutions | Kempton Park | Stationery and Office consumable Wholesaler | |
| dmg Events | Johannesburg | Exhibitions | |
| DMH Talent Agency | Cape Town | Talent Management/Models/Actors/Singers/Dancers | |
| DMME Translation Services | | Professional translation and editing services | |
| DMV Architecture | Port Elizabeth | Architecture, interior design, project management | |
| DNA Cleaning | Cape Town | Selling of natural cleaning products | |
| DNA Community | Cape Town | Business and Growth Hacking | |
| DNA Healtjh | Johannesburg | Cold Press Juicers and Super Blenders | |
| DNA Studios | Cape Town | film, television, corporate videos & animation | |
| DNA Test | Boulevard Umhlanga | Forensic and Relationship DNA Testing | |
| DNR Auto AND Roadside | paarlshoop | LOCAL AND LONG DISTANCE TOWING. MEDIUM AND HEAVY T | |
| Doan Restoration of MichiganMI | Port Huron | Water damage restoration service | |
| Doctor Debt | Scottburgh | Debt Review | |
| Doctor Fix-It Plumbing, Heating & Electric | Denver | Plumber | |
| Doctortajmel.com | | Mumyaznet | |
| DoDo Safety and Industrial | Johannesburg | Safety Inspections and PPE | |
| DogOnline | Randpark Ridge | DogOnline Exclusive Pet Store | |
| Dolfin SEO | Beaufort | Marketing, SEO, Web Design, Digital Marketing | |
| Doll Communications | Pretoria | Branding and events | |
| Dolsin Business Solutions | Roodepoort | Online Communication & Marketing tools for SME's | |
| Domestic Aid | Ekurhuleni | Direct marketing | |
| Domestic Garage Doors | Boksburg | Garage door repairs, maintenance and service | |
| Domestic Support | | Employer & Domestic Worker Services UIF and more | |
| Domyassignmentpro | | Digital Marketing | |
